Genomic instability is the main causal factor of aging and many external factors beyond our control accelerate it as all those contaminants in the environment that cause DNA damage, and it is important to regularly ingest the nutrients that have been shown to help repair DNA damage and reduce cell mutations to keep the body young, healthy and beautiful.
Aging is deterioration of the organism and there are common denominators of aging called Hallmarks of aging. These hallmarks are: genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, deregulated nutrient sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and altered intercellular communication. From all those Genomic Instability is considered the primary cause of aging and cancer development.
As a anti aging coach I guide people to avoid certain carcinogens as canned food, alcohol, hydrogenated oils, refined sugars, GMOs, or even microwave popcorn. But we are in a world where most people ignore how harmful are those products, even most doctors. So they are everywhere and often in restaurants we order something without knowing what is included in the ingredients. So consuming the next nutrients can be important to avoid being affected.
I’m going to talk about these compounds from plants that can be taken in supplementation that have been proven to protect your DNA from damage, which correlates closely with how long you will live and also about something so complex as genomic instability. Consuming these supplements can be helpful when you go to a restaurant, or when you eat those cancer-causing grilled foods or microwave popcorn as well when you drink alcohol.
What is Genomic Instability ?
Genomic Instability is when there is accumulation of DNA damage that cause tissues and body processes become dysfunctional, as result the body deteriorates. When cells divide they replicate the DNA and sometimes the make mistakes, the DNA is not replicated correctly and a mutation occurs. The content and information of the genome is changed. This happens very day but the has processes body to fix the problem with success.
As we age, the body is less successful at repairing those mistakes and the cells are replicated with mistakes in the DNA and the accumulation of these cells with the wrong transcription of the DNA is called genomic instability. Those cells are mutations and your body have 3 processes to deal with them, Autophagy, Apoptosis, and Cycle Arrest.
Autophagy is when these damaged proteins inside the cell are broken down in amino acids and from them is to build up new proteins and the cell can continue living properly. But if the problem is not fixed and the cell continue with its malfunction the body program the cell death, what is called apoptosis. The cells it is killed and it is replaced from the stock of stem cells. Often cells avoid apoptosis, do not die and the body forces cell cycle arrest. Which is when the cell can not divide anymore and become senescent cell.
How to prevent DNA damage?
Detoxifying your body and avoiding dietary carcinogens is a good way to start. Canned foods can be replaced by foods packaged in glass, hydrogenated oils by coconut oil, avocado oil and olive oil that also have anti-aging properties. If you drink alcohol or eat grill foods that are carcinogenic and they damage DNA, you can consume the following compounds.
Xanthohumol is a natural hops-derived flavonoid compound that has been shown in clinical human studies to reduce DNA damage in cells. Chlorophyllin which is the water-soluble version of chlorophyll have been recognized for their multitargeted capacity to reduce DNA damage as well as Watercress in extract. The last nutrient is Chlorella growth factor. An amazing nutrient complex found in the cell nucleus of chlorella that would help repair damaged genetic material in human cells, thereby protecting health and slowing the aging process. I’m going to talk about each nutrient and how they benefit DNA below.
